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The Effect of LISTERINE® Antiseptic Mouthwash on Reduction of Existing Plaque and Gingivitis1
Evaluate the effect of LISTERINE® Antiseptic on existing dental plaque and gingivitis over the course of a 6-month trial (N=129).
Randomized, double-blind study of subjects (aged ≥18 years) with preexisting plaque and gingivitis.
When compared with water, LISTERINE® Antiseptic reduced dental plaque by 22.2% and gingivitis by 28.2% at 6 months. When compared with vehicle, LISTERINE® Antiseptic reduced dental plaque by 20.8% and gingivitis by 27.7% at 6 months, respectively.
LISTERINE® Antiseptic, when used twice daily for 30 seconds, is effective in controlling plaque accumulation and gingivitis in a population that did not receive a prophylaxis.
*LISTERINE® Antiseptic is not indicated for use in the treatment of xerostomia.
†Subjects were instructed to follow their usual oral hygiene regimen and use of dental floss was permitted to remove trapped food.
‡26.9% hydroalcoholic vehicle containing all ingredients in LISTERINE® Antiseptic except its essential oils.
Reference: 1. Lamster IB, Alfano MC, Seiger MC, Gordon JM. The effect of LISTERINE® Antiseptic on reduction of existing plaque and gingivitis. Clin Prev Dent. 1983;5:12-16.