Comparative Effects of 2 Chemotherapeutic Mouthrinses on the Development of Supragingival Dental Plaque and Gingivitis1,2
PeridexTM vs LISTERINE® for Gingivitis and Dental Plaque
Determine the efficacy of 2 mouthrinses—LISTERINE® Antiseptic and Peridex™—used as supplements to regular oral hygiene measures in reducing supragingival dental plaque and gingivitis (N=124).
Double-blind, controlled, parallel design clinical study of healthy male and female subjects (aged ≥21 years) with preexisting plaque and gingivitis but without evidence of periodontitis.
At 6 months, gingivitis development was inhibited by 35.9% in the LISTERINE® Antiseptic group and by 30.5% in the Peridex™ group, when compared to the hydroalcohol control (P<0.001).
At 6 months, gingivitis development—in posterior regions—was inhibited by 33.2% and 34.4% in the LISTERINE® Antiseptic group and by 26.6% and 33.8% in the Peridex™ group, when compared to the hydroalcohol control (P<0.001).2
LISTERINE® Antiseptic produces gingivitis reductions comparable to Peridex™ at 6 months (including gingivitis in posterior regions).