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Technical Innovations

LISTERINE® Antiseptic Germ Kill

LISTERINE® Antiseptic Germ Kill

LISTERINE® Antiseptic rinses kill bacteria to penetrate plaque biofilm

AT FULL STRENGTH, LISTERINE® ANTISEPTIC HAS A BROAD SPECTRUM OF BACTERIAL KILL

LISTERINE® Antiseptic lyses, kills, and inhibits growth of both gram-positive and gram-negative bacteria.1-7 The superior antimicrobial actionDESTROYS the bacterial cell surface,9  INHIBITS biofilm growth,9 and INCREASES the time it takes for bacteria to grow back.10

Specifically, LISTERINE® Antiseptic kills:

Gram-Positive Bacteria (+)
Actinomyces naeslundii
Actinomyces viscosus
Staphylococcus aureus
Streptococcus mutans
Streptococcus sanguinis
Lactobacillus acidophilus
Enterococcus faecalis*
Streptococcus pyogenes 
Streptococcus gordonii

Gram-Negative Bacteria (-)
Aggregatibacter actinomycetemcomitans
Porphyromonas gingivalis
Prevotella intermedia 
Bacteroides loescheii
Eikenella corrodens
Fusobacterium nucleatum
Klebsiella pneumoniaue*
Leptotrichia buccalis 
Pseudomonas aeruginosa*

Gram-Neutral Bacteria
Candida albicans (yeast)11

30 Second Rinse

30-Second Rinse

Find out how LISTERINE® Brand rinses clean the mouth in 30 seconds
RAPID FUSION TECHNOLOGY™

RAPID FUSION TECHNOLOGY™

Formulated to provide greater fluoride uptake

LISTERINE® ANTISEPTIC GERM KILL - footnotes/references

<span class="indent-sub">*</span>Tests were run at 1-minute time point.<br /><br /> <strong>References: 1.</strong> Fine DH, Letizia J, Mandel ID. The effect of rinsing with Listerine antiseptic on the properties of developing dental plaque. <em>J Clin Periodontol.</em> 1985;12:660-666. <strong>2.</strong> Ricci-Nittel D, Fourre T. In vivo evaluation of antimicrobial activity of an essential-oil mouthrinse. Presented at: General Session of the International Association for Dental Research: March 16-19, 2011; San Diego, CA. <strong>3.</strong> Ross NM, Charles CH, Dills SS. Long-term effects of Listerine antiseptic on dental plaque and gingivitis. <em>J Clin Dent.</em> 1989;1(4):92-95. <strong>4.</strong> Drake D, Villhauer AL. An in vitro comparative study determining bactericidal activity of stabilized chlorine dioxide and other oral rinses. <em>J Clin Dent.</em> 2011;22(1):1-5. <strong>5.</strong> Andreana S, Nittel-Ricci D, Wu MM, Harper DS, Baxter KA. In vitro antimicrobial activity of vanilla mint Listerine® antiseptic mouthrinse. Presented at: IADR/AADR/CADR 85th General Session and Exhibition. March 2007. <strong>6.</strong> Pan PH, Finnegan MB, Sturdivant L, Barnett ML. Comparative antimicrobial activity of an essential oil and an amine fluoride/stannous fluoride mouthrinse in vitro. <em>J Clin Periodontol.</em> 1999;26(7):474-476. <strong>7.</strong> Fine DH, Furgang D, Barnett ML, et al. Effect of an essential oil-containing antiseptic mouthrinse on plaque and salivary Streptococcus mutans levels. <em>J Clin Periodontol.</em> 2000;27(3):157-161. <strong>8.</strong> Pan PC, Harper S, Ricci-Nittel D, Lux R, Shi W. In-vitro evidence for efficacy of antimicrobial mouthrinses. <em>J Dent.</em> 2010;38(suppl 1):S16-S20. <strong>9.</strong> Fine DH, Furgang D, Lieb R, Korik I, Vincent JW, Barnett ML. Effects of sublethal exposure to an antiseptic mouthrinse representative plaque bacteria.<em> J Clin Periodontol.</em> 1996;23(S):444-451. <strong>10.</strong> DePaola LG. Safety and efficacy of antimicrobial mouthrinses in clinical practice.<em> J Dent Hygiene.</em> 2007 (special suppl);13:13-25. <strong>11.</strong> Meiller TF, Kelley JI, et al. In vitro studies of the efficacy of antimicrobials against fungi. <em>Oral Surg Oral Med Oral Pathol Oral Radiol Endod</em>. 2001;91:663-670.