NEUTRALIZING TECHNOLOGY

THE ROLE OF VOLATILE SULFUR COMPOUNDS IN ORAL MALODOR

Although many factors contribute to oral malodor, most cases typically result from the activity of bacteria in the oral cavity.^2,3 Oral bacteria break down organic materials (amino acids and peptides) and food debris in the mouth through a process called bacterial putrefaction.² The result of this putrefaction is the production of volatile sulfur compounds (VSCs).² VSCs, in particular hydrogen sulfide, methyl mercaptan, and dimethyl sulfide, are a primary component of oral malodor.⁴

The highest concentration of VSC-producing bacteria occurs primarily at the back of the tongue, past the circumvallate papillae.^2,4 It's difficult to reach this posterior segment, even with manual cleaning methods, including tongue scrapers.⁵

LISTERINE^® READY! TABS™ DELIVER A CLEAN-FEELING MOUTH AND LONG-LASTING FRESH BREATH¹:

• By neutralizing VCSs in the mouth using a proprietary technology¹
• By accessing hard-to-reach areas, including the back of the tongue, through its unique ingestible formulation¹

LISTERINE^® READY! Tabs™ bind to odor molecules and change their molecular structures, thereby helping to eliminate oral malodor

LISTERINE^® READY! Tabs™ transform from a solid to a liquid in seconds when chewed. They are designed to freshen breath on the go, when sink-based oral hygiene routines are not an option.¹

THE EFFICACY OF LISTERINE^® READY! TABS™ WAS ESTABLISHED IN A RIGOROUS CLINICAL STUDY¹:

LISTERINE^® READY! TABS™ were studied in a clinical trial of 79 patients.¹ Each subject's breath was tested using:

• By neutralizing VCSs in the mouth using a proprietary technology¹
• By accessing hard-to-reach areas, including the back of the tongue, through its unique ingestible formulation¹

Assessments were conducted at baseline, immediately after use, and at 1-hour intervals for 4 hours.¹

LISTERINE^® READY! TABS™ IMMEDIATELY TREAT MALODOR AT THE SOURCE FOR NOTICEABLY FRESH-SMELLING BREATH LASTING UP TO 4 HOURS¹

Organoleptic results:
Fresh-smelling breath for up to 4 hours

P<0.05 versus control; statistical significance was achieved at all post-baseline time assessments.

P value for between-treatment comparisons is based on a mixed model for repeated measures (MMRM) with baseline as a covariate.