Lamster IB et al (1983)

THE EFFECT OF LISTERINE^® ANTISEPTIC ON REDUCTION OF EXISTING PLAQUE AND GINGIVITIS¹

Objective
To determine the efficacy of LISTERINE^® Antiseptic as an adjunct to normal oral hygiene in reducing existing plaque and gingivitis over a 6-month period.

Methods
In this 6-month, randomized, double-blind, supervised, controlled clinical trial, all 129 subjects completing the trial had preexisting plaque scores >1.8 using the Turesky modification of the Quigley-Hein index and preexisting gingival index scores > 2.0 using the noninvasive Modified Gingival Index.

Subjects rinsed twice a day with 20 mL of either LISTERINE^® Antiseptic or its vehicle control (26.9% hydroalcohol) in addition to their usual oral hygiene. Soft bristle toothbrushes and nonfluoridated, low-abrasive toothpaste were supplied. Use of dental floss was permitted. Subjects were asked not to use mouthrinses, other than those provided for the study, or oral hygiene devices. No dental prophylaxis was performed prior to treatment. Plaque, stain, gingivitis, and oral soft tissues were evaluated at baseline and at 1, 3, and 6 months.

Results
The LISTERINE^® Antiseptic group had a 20.8% reduction in plaque scores and a 27.7% reduction in gingivitis scores compared with the vehicle control group at 6 months.

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REFERENCES

1. Lamster IB, Alfano MC, Seiger MC, Gordon JM. The effect of Listerine Antiseptic on reduction of existing plaque and gingivitis. Clin Prev Dent. 1983;5:12-16.