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Here are answers to some of your questions about oral care products.

1. What are the general benefits of each mouthrinse in your product line?

We offer a full line of rinses developed by scientific technology for superior efficacy to help your patients.

  • LISTERINE® Antiseptic products help prevent and reduce plaque and gingivitis
  • LISTERINE® TOTAL CARE is a multi-benefit mouthwash that works in 6 ways for a cleaner, healthier mouth:

1.Helps prevent cavities

2.Restores enamel

3.Strengthens teeth

4.Freshens breath

5.Kills bad breath germs

6.Cleans the whole mouth

  • LISTERINE® WHITENING® products help promote whitening
  • LISTERINE® ZERO products offer an alcohol-free option to killing germs that cause bad breath for a cleaner, fresher mouth
  • LISTERINE® KIDS products aid in the prevention of dental cavities (LISTERINE® SMART RINSE®) as well as help kids develop proper oral care habits (LISTERINE® AGENT COOL BLUE®)

You can find more information about LISTERINE® Rinses within our Rinse page of our Web site.

2. What is the Safety of LISTERINE® Antiseptic?

LISTERINE® Antiseptic Mouthwash is the world's most clinically studied mouthwash for daily, long-term use, with more than 50 clinical studies examining its safety and efficacy. LISTERINE® Antiseptic Mouthwash is also the world's number one dentist-recommended brand of over-the-counter antimicrobial mouthwash and has been used safely by over one billion people and has been on the market for more than 125 years. You can find more information about LISTERINE® mouthrinses within our Journal Library.

3. What are the active ingredients in LISTERINE® Antiseptic?

Menthol, thymol, methyl salicylate, and eucalyptol. See for yourself how the unique formulation within LISTERINE® Antiseptic penetrates to kill plaque biofilm.

4.What are the roles of alcohol in some LISTERINE® mouthrinses?

Alcohol has many roles in LISTERINE® Antiseptic:

  • Solvent
    • Helps to solubilize ingredients
  • Vehicle for active ingredient:
    • Enables penetration of the 4 Essential Oils into plaque biofilm, or bacterial communities
  • Preservative
    • Prevents microbial growth and maintain product stability

Read numerous published and peer-review abstracts discussing the usage of alcohol-containing mouthrinses in our Journal Library.

5. Do alcohol-containing mouthrinses promote oral dryness or oral cancer?

Since the 1970s, scientists have compiled an extensive body of clinical data that concludes there is no evidence that alcohol-containing mouthwashes cause oral cancer. Leading experts agree: available evidence does not support a causal association between mouthrinse use and risk of oral dryness or oral cancer.

Read numerous published and peer-reviewed abstracts discussing the usage of alcohol-containing mouthrinses in our Journal Library.


LISTERINE® ZERO provides a deep clean, with less intensity and zero alcohol, for a cleaner, fresher mouth. The product is intended to provide your patients seeking fresher breathe with the less intense option of a non-alcohol containing mouthwash in the LISTERINE® line of products. No other alcohol-free mouthwash has been proven more effective at killing bad breath germs than LISTERINE® ZERO.

7. What are the benefits of using LISTERINE® TOTAL CARE Anticavity Mouthwash?

No other OTC fluoride mouthwash is more complete than LISTERINE® TOTAL CARE Anticavity Mouthwash. LISTERINE® TOTAL CARE Anticavity Mouthwash provides the following benefits:

  • Helping to prevent cavities
  • Restoring enamel
  • Strengthening teeth
  • Killing bad breath germs
  • Freshening breath

8. What is the active ingredient in LISTERINE® TOTAL CARE Anticavity Mouthwash?

Each dose of LISTERINE® TOTAL CARE Anticavity Mouthwash contains 0.02% sodium fluoride. For a deeper understanding of how LISTERINE® TOTAL CARE Anticavity Mouthwash boosts fluoride uptake in tooth enamel, watch our RAPID FUSION™ Technology video.

9. Why is LISTERINE® TOTAL CARE Anticavity Mouthwash a twice-daily rather than a once-daily rinse?

LISTERINE® TOTAL CARE Anticavity Mouthwash should be used twice daily as part of a standard oral care routine of brushing, flossing and rinsing. The 0.02% sodium fluoride concentration contained in LISTERINE® TOTAL CARE Anticavity Mouthwash provides its full anticavity and enamel strengthening benefits when used twice daily as directed.


LISTERINE® SMART RINSE® is an anticavity fluoride rinse designed to help clean and protect kids' mouths beyond brushing alone. Unlike other rinses, SMART RINSE® protects kids' teeth from cavities and works like a magnet to attract the particles that brushing may leave behind and tints the particles, leaving proof in the sink of a cleaner mouth for parents and kids to see. LISTERINE® SMART RINSE® does not prevent or reduce plaque or gingivitis.